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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6dce212fa9c356e6e28c59afa1a9c2201993b3f0600cff917c8d3b451ffa7c' 
  AND token = 'oVTlyDUwY/3nG8nHKgxoS1E49GIh1cwfMePgth0Tvxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}