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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e67e819ce32642d2a25152ebc820d3879b893b0537492e7f7840301fd7c950a' 
  AND token = 'KRZW8UbaM/+2D5OZSImWhv8gUfEiEms7CyynU0HcrOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}