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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4174a72bca9da14235fb2328cb4bcc17b0ab868a822a37a40fccaf3256b99001' 
  AND token = 'J/Pi+JfUnZqTInaMiZ51x3lS2JOaw9uEzcNr6nj4x4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}