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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6be3ff21f4bb2d384cd4ac9734739b366bdc8aee951183f39209f9b430f98be2' 
  AND token = 'T915RRq46X8+wSWzfI2YK0JfZBRiYI+0GwlUTge0aLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}