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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8b1acdff4f6721dd2f4adf2c737492d890c84dfb672a44403cedb301b15a792' 
  AND token = 'RDUhnx6aCX7UD0mlSWl325+jRq4PnKyZuCdXfbqNYWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}