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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3c39428e02b96e2749c377d470e3020093e28c7a6945d955289e1d917dbf763' 
  AND token = 'D702c7fZ/2AZ65Z3nofphk468bPI80m1sBFZaZtPmCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}