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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a145f0332c7f04330337d0a9c4447f261484bb133fbf4a1309c478c74844dd' 
  AND token = 'vd6SLMYx72MBIWy4Qk+RP9UR6S20bxRUVOb5xm+7qxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}