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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e14b4848423224ea0c602e71e96a8efa39e54e6cca6d7907772003712435d28' 
  AND token = '6IwewkbHc9yB8D+cX+VKjejdD/uWmmiIqM1eWN688qI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}