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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb367f38d6721bdadb48a9d2972521c12da6080c70fa48e548d5b007e6b3b12f' 
  AND token = 'n8wBNAdvSwDjP2iLUvS6e9YqORARmT8qAkh28RFk+cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}