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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e06a6453c3480fd56c9589fc46e6b59bfcf00c440df74c02c4e762deec4d71f' 
  AND token = 'WZ5Zp3mI54XnCdkiQdBEr4MT3fpqLu6SJGMR9gPHFaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}