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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817a276eb955718a8e6bcaab6eabce13ad019d9e6c0c09cbf4f2161a2f0061f8' 
  AND token = 'mVXm2VJuU3fv1AOceZmAxv2+R0xf8rVW/Z9YkbVB8xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}