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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79a320d935b8a6945861dc7ddd555fe754fa3906e9adce73668e8f73830da1d6' 
  AND token = 'qjNPiA565HxZ3x6xxUgEN+UjWgSLISMaybymXD4Myeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}