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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb6613642299cf7b849bdba6e7113e727d8a1433510717781fa05bc7428ad21' 
  AND token = 'Im41Nu8v1ONZ1DT+VGFx3xN0URTjuBtY1Nocx+IobZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}