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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed60a38d9e05810a30c9f0528e1d6d90877f94c2382139a55df2ea7d54491f04' 
  AND token = 'NRvzP+c0gDgUm9ZTqgKVMTSUf3kXMFhVRrdPrihOKoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}