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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c493164a9e73524a16d5c8e20a96c952c5beb2db1c1daab6b5434e26afa886' 
  AND token = 'OPJsnVWrk6jewGecADnJLJWRYnR5H8wsDvPALfwpaak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}