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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25324fa252f7c890bf3081063d95c180fc89ade9e5072147e590cdc5fd086a9' 
  AND token = 'jS0k4spuggcpW3FN+uD2nNgc/M82fbTreWS0VafUcGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}