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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ef44b11ec8c998307d13d8f67c18e44746d5b97071c76e9cba7f682e266c8c' 
  AND token = 'IBRj1kLMwF5IpKy/r2zNr/MdHHZ3RsADBIOdgNNRUTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}