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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d5abe9d83dc3a9a9b384feeb93138569507f9c18d3c893e6884c18635863def' 
  AND token = 'X2EV6xCc1r8dkEPCsuamUsDxVccPt0Vw2xOKvmjuF1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}