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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e638435b43298841b9826e44ae14e3e6e87d3b93da49dfe53f1118d94ee82220' 
  AND token = 'zbwAXNqe+x58YEJZw6qobkbnyjoJe3jCO/vDwKNWzrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}