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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c120eb7803903a58f8530d6f18a30de2a5b2400abda8aea5dc93390e2f0380' 
  AND token = 'vmx8BUHt4fFEvZR0ht+YMY3e4Z0iQvJl86gHn3HF10M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}