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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03a1d4b010e15be92c48743d48a5376a50fd4d514d21779bd3a63190ebc92c40' 
  AND token = 'CncwnW9dpFQSmERyel2v6K9ZKZNjUCOXWKQabnLTwJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}