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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29d5a93c944edba965fbb7d58fc9298d6559bf05bcc870040e7aabefcd4bb60' 
  AND token = 'Q+dp3yuECfGUe41dQxsHGzTKXuKOCTLWm/tpGY5zd5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}