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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '843a9d2dd83c333fd4d605c54da7eae432b5fab4e1e0eda7ce98df9336181410' 
  AND token = 'knHlfVcmezSH9NmGw195UHtVnKPFArLG0ioCYg2n7UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}