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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '418906c89dcee4731ff94c18afc7e26d6d4c1385570b75fc879e8b946f2a8548' 
  AND token = 'IhB8euvU2Si3XEBE8sSdjOtaY73P3RmAKXxc5AJuuxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}