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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580d4a6018d9d87d99e5766fbb26202a6d5dccd72d5af3692c38cd107af74fe6' 
  AND token = 'KHC0A/vVdy8ktIbThdxiWcLwXVHTWMjU9vrOgSk2pmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}