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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ba7c241502f6a001c485bbdcf569198bdd3c150e164490392215f3da64c6c7d' 
  AND token = 'FvC3G9xxMsPEOJdkB+urOvGjN5yyzbFrCPwI7Lsm2+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}