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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3527b540d58aef5480e20f5500dc592bf0f970d064436dd682bfffc0f179ce' 
  AND token = 'VLmlbEXk5Liowcw/5sONVRDET3z+WGTSnCaMO280mLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}