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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd59c3a0a0f996c6c51e04b6bee30c006d9a8f9b2396045ced98eeabec003bb1' 
  AND token = 'Y/NgOX48OwQlACdjV4t7WaAuUz6/oAwFBYCVPQdId+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}