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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e330feea80a3d14a56bf968232c2e0117c2a7c43a8e5a2ba88de62424bcdb8d2' 
  AND token = '1EZOS+Lz5XxZedlixYhddGJbow4dJhts84THxPoXJdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}