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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f9245c6b67e443acc6ca71426c23fa24efe5ca10222af2b7ffe2c37ae45081d' 
  AND token = 'opyQVCA1+6k7p76EGld6VF3NGinu/mkqsMYT9zcAh1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}