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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f363a72fb8215bd54ffa71f3436352cb5a78435e2bd55c212d56f0fbfea9a96c' 
  AND token = 'zL+P3U/A02xSWlTjZXxN7Q3UmwEK+1S8K6d7y+zDaVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}