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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ef4fb4c6f984a304c0b3eb390e6b5db0564e5600be8efb4d95bc21eb31c430' 
  AND token = 'O6ZTHunicKyR8Z8AEatKswGlfpxUg+ynQfA6AnGt8IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}