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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c461124b7bd34932a77e2b3633e32d5376d5188e23b3c3de99f375181acb24' 
  AND token = 'geHPN32LyOqsP7Jj/D+FWAVQtbaYxyki2yfTRXls3EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}