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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8225eadd77619ab59d7022a4d208979ae1b1cf7370be3e1ba391e0e381ee1fa3' 
  AND token = 'xtehbTmPXo0HZ7homMVw/l6S1PL6NsWW9KUq0ZWauxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}