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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6efdce03175747612a40567c1ac271b155d9214cd116479c6671b017e6be2e6d' 
  AND token = 'B4d9Do8Zyn+jH1cvW9pwKkwP0qateEBcuXTc5GeojrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}