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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb6f063a6d52a64dd11ac5130435d6b10e2c9bf1656f5ce3083856a66a5bd87' 
  AND token = 'XdmtPhDBBaY1Hnw3rEFZgc4VF8K41OmPl+cdmBdc43w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}