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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5cdcaa63429b1012d7ef4c5e078d74f8536e193c256039ab283781375b1c006' 
  AND token = 'S9UsL6ykfFpgVbjSZYAcNsn9D7ue0/FcRTEmd+eWd0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}