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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f045c39f0b45bdb0108070da56c9a225d3c418a0e03205d7a02c2532560f387' 
  AND token = 'LfOkwsiRvkl8kjVSKLDSe00ZXwmIHdvrGA4qh18DVlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}