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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39bc9bfca7c6bb710ad595e12751b7fce89280ab9511f3b8af41e3aff8b75347' 
  AND token = 'Zli8uMMr+SG/0uw5UmPpgcI8YeS1wlFPQJe/yJzKPo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}