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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0af9e5bdfeb77e37e5ddf732a06071326e9fbfa72a33ec307a8f8a249e72c2' 
  AND token = 'qJuvEiuQKJmw9rTDZQ6GrGhtm3jWZ4pH1rZpdNegO/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}