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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b90f8005a3dc77e93b32138c72357af28183050b132ffe78df56ac84575e0e' 
  AND token = '7ayakcOSESK+vSMszvm54Kuidk+69L3/3LYN1OF7so4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}