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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd342c7ea312a72b55339b79118dbc47ecddefe1ff38e9af496f6b49567023e1b' 
  AND token = 'wMFbWeTOwUHR+d4pM60q3taOuT7AZkWd51j73gu7Gp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}