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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ad8f677d8070dafe563cf43f064d870de7c3cac41cbe825229532489629dad' 
  AND token = '6o43N2//dkq5tS5A9zX/n/P5fY8zFRiTXdwfa9I/+3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}