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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8febaa7bbc254a5496ff5a55826f07116d282f21195d360345da9044045a806' 
  AND token = 'VOxqTSdx+pmhsNGAIDQUIWxE3iA8gC6Ed4G0eN+2t8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}