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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c123dc487a8e25ac4fe9b8168e6bbc6e861f39f8fb7c56649ed625f0e9fe864' 
  AND token = 'ndWA9B2mNFib8LE1z4OCwyxPUI+4jJK0oL8Tv99J5Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}