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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f61a1c88906d026c22897b2375fc856c655f6303f611bf0a09578339386e3091' 
  AND token = 'LUXp1zr1un2t52Y5BowV3eLRs/TcMRnvBUBktwdCcJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}