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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6bc57c3593535e11a6b14b9858305c7ed91a427d6d9cf0179f4de6639bf68b1' 
  AND token = 'CAWO/a1YETCGsk9LQ4Q04dwCl712s/vjvWPcwUWaIFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}