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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d18dc872ba06a59eaad820867efeabebcbfd0d33aa93a041381a9d927f8cf58' 
  AND token = 'lSMTrZCXBUOaS/Frwdo7tGWFc2lDEeb9j1ds/q4zITc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}