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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a5a6cabc1e565a5a2866e30410670de9d5cbaf90d90932760bc0fb2e52ca56' 
  AND token = '5EPDFc5KgTtSdRjjdsWOuDR1RsgMaiehiRuCPPlkxzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}