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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fa2f6e56928fa51b53d724920f89b22ccb621beac0f010804a28540fef946b0' 
  AND token = 'MRLiuF4asTZ+UhHvOE4TqDxZd6x0nbBtPmo1zzSZxh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}